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. 2018 Jul 19;9:959. doi: 10.3389/fphys.2018.00959

FIGURE 1.

FIGURE 1

Energy production in immature cardiomyocyte. Carbohydrates are the main substrates for energy production of the immature cardiomyocyte. About 50% of ATP production derives from anaerobic glycolysis which also produces pyruvate that can be used by mitochondria to generate energy from oxidative phosphorylations. Lactate that is in high concentration in the fetal blood participates in energy production through its conversion to pyruvate. Energy is essentially produced in the form of ATP molecules which diffuse within the cytosol to reach ATP consumers of the cell. CD36, fatty acid translocase; GLUT4, glucose transporter 4; MCT, monocarboxylate transporter; ATP, adenosine triphosphate; ADP, adenosine diphosphate; NAD and NADH, oxidized and reduced nicotinamide adenine dinucleotide; FAD and FADH2, oxidized and reduced, flavin adenine dinucleotide. Acyl-CoA, acyl-coenzyme A.