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. 2018 Jul 19;9:889. doi: 10.3389/fphys.2018.00889

FIGURE 5.

FIGURE 5

Ductal CBE activity was mediated by CaMKII. (A) The effect of KN-93 (20 μM) on CBE activities of AE2 and SPL co-expressed cells for 1 h in HEK293T cells. (B) Bars indicate the means ± SEM of the number of experiments (∗∗P < 0.01, n = 4). (C) Changes in pHi of isolated SMG acini and ductal cells with and without KN-93. (D) Bars indicate the means ± SEM of the number of experiments (∗P < 0.05, n = 4). (E) Figures represent the inhibition model of Cl− flux by KN-93. (F) Changes Cl− transporting activity by KN-93 (20 μM) with MQAE technique in isolated SMG ductal cells. (G) Bars indicate the means ± SEM of the number of experiments (∗P < 0.05, n = 4).