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. 2018 Jul 19;9:1627. doi: 10.3389/fmicb.2018.01627

Figure 5.

Figure 5

The cationic amphiphilic indolyl Mannich base 4 is a membrane targeting mycobactericidal agent. Cationic amphiphilicity is absent in 5, 6, 7a, and 7b which are deconstructed analogs of 4. They have poor antimycobacterial activities.