Table 6.
Univariable binary logistic regression results identifying predictors of progressive CKD within the first 12 months of diagnosis of azotemic CKD in cats
| Univariable analysis | Stable (n = 50) | Progressive (n = 29) | n | OR (95% CI) | P |
|---|---|---|---|---|---|
| Normomagnesemia | 48 (72) | 19 (28) | 67 | .010 | |
| Hypomagnesemia | 1 (12) | 7 (88) | 8 | 17.68 (2.04–153.59) | .009 |
| Hypermagnesemia | 1 (25) | 3 (75) | 4 | 7.58 (0.74–77.48) | .088 |
| FGF23 (pg/mL) | 459 [334, 1037] | 1944 [575, 5761] | 79 | 1.90 (1.29–2.80) | .001 |
| PCV (%) | 34 [32, 37] | 30 [25, 34] | 79 | 0.87 (0.79–0.96) | .004 |
| Creatinine (mg/dL) | 2.37 [2.23, 2.80] | 2.69 [2.39, 3.77] | 79 | 2.65 (1.26–5.56) | .010 |
| Phosphate (mg/dL) | 4.38 [3.50, 5.09] | 4.95 [3.95, 6.05] | 79 | 1.33 (1.01–1.74) | .043 |
| Albumin (g/dL) | 3.2 [3.1, 3.3] | 3.0 [2.8, 3.2] | 79 | 0.19 (0.04–0.95) | .043 |
Only log‐transformed plasma FGF23 concentration remained an independent risk factor for progression with multivariable regression. Group characteristics are reported as number (%) or median [25th, 75th percentiles].
Abbreviations: 95% CI, 95% confidence interval; FGF23, fibroblast growth factor 23; OR, odds ratio; PCV, packed cell volume.