Table 3.
Hazard ratios and 95% confidence intervals for stroke by 2 models1 and 3 methods according to quintiles of the first dietary pattern score in 5,468 males and females from MESA
| Quintile 1 | Quintile 2 | Quintile 3 | Quintile 4 | Quintile 5 | p for trend2 | |
|---|---|---|---|---|---|---|
| RRR 1 | ||||||
| Model 1 | 1.00 (reference) | 5.69 (1.27, 25.46) | 4.84 (1.06, 22.16) | 5.97 (1.32, 27.02) | 7.49 (1.66, 33.69) | 0.01 |
| Model 2 | 1.00 (reference) | 5.66 (1.26, 25.38) | 4.87 (1.06, 22.34) | 5.97 (1.31, 27.07) | 6.83 (1.51, 30.87) | 0.02 |
| PCR 1 | ||||||
| Model 1 | 1.00 (reference) | 1.07 (0.40, 2.86) | 2.51 (1.07, 5.87) | 1.03 (0.35, 3.01) | 1.45 (0.54, 3.91) | 0.45 |
| Model 2 | 1.00 (reference) | 1.16 (0.43, 3.11) | 2.65 (1.13, 6.18) | 1.10 (0.37, 3.23) | 1.47 (0.54, 3.96) | 0.44 |
| PLS 1 | ||||||
| Model 1 | 1.00 (reference) | 2.46 (0.87, 6.92) | 2.13 (0.72, 6.25) | 3.14 (1.10, 8.97) | 2.07 (0.65, 6.59) | 0.17 |
| Model 2 | 1.00 (reference) | 2.51 (0.88, 7.09) | 2.18 (0.74, 6.45) | 3.08 (1.07, 8.88) | 2.02 (0.63, 6.64) | 0.20 |
MESA, Multi-Ethnic Study of Atherosclerosis; RRR 1, the primary factor derived by, reduced rank regression; PCR 1, the primary factor derived by, principal component regression; PLS 1, the primary factor derived by, partial least squares.
Cox proportional hazard model adjusted for sex (male or female) and race (White, Black, Chinese or Hispanic) in model 1 and also adjusted for sex, race, smoking (never, former or current), physical activity (total intentional exercise) (MET-hr/wk), family history of stroke (parent) (no, yes, or don’t know), family history of stroke (sibling) (no, yes, not applicable, or don’t know), any lipid-lowering medication (yes or no), any anti-hypertensive medication (yes or no), hypertension (yes or no), and myocardial infarction (yes or no) in model 2.
p for trend was obtained by treating the score variable as a linear term.