Table 1. . Burden of antimicrobial resistance rates reported in typhoidal Salmonella from Indian studies of past 15 years.
Antibiotic | Salmonella Typhi | Salmonella Paratyphi A |
---|---|---|
Ampicillin† | 5–72% | 0–74% |
Chloramphenicol† | 3–27% | 0–23% |
Cotrimoxazole† | 2.3–35% | 0–36% |
Nalidixic acid | 78–100% | 63–100% |
Ciprofloxacin‡ | 0–97% | 0–100% |
Ceftriaxone | 0–4% | 0–6% |
†MDR S. Typhi classified based in resistance to ampicillin, chloramphenicol and cotrimoxazole is coming down in the recent years.
‡High rates of ciprofloxacin resistance is due to the revised breakpoints in the CLSI guideline.
Refs: [23–29]
CLSI: Clinical and Laboratory Standards Institute; MDR: Multidrug-resistant.