Figure 2.
(A) Cardiac index of candidates supported by an IABP at the time of listing. The histogram on the left is of cardiac indices for candidates without circulatory support at the time of hemodynamic measurement. The histogram on the right is of cardiac indices of candidates supported with the listing IABP at the time of hemodynamic measurement. The vertical lines represent the cutoff for cardiogenic shock, 2.0 liters/min/m2 for candidates without mechanical support at the time of listing and 2.2 liters/min/m2 for candidates supported by IABP. Candidates to the right of the line would be ineligible for Status 2 listing. (B) Cardiac index of candidates supported by high-dose single inotropes or multiple inotropes at the time of listing. The cardiogenic shock cardiac index criterion (<2.2 liters/min/m2 when supported by inotropes) is marked with a vertical line. Candidates to the right of the line would be ineligible for Status 3 listing. Candidates supported by multiple inotropes had a higher cardiac index (mean 2.24 liters/min/m2 vs 2.16 liters/min/m2; p = 0.018) and were more likely to be ineligible by shock criteria for Status 3 than candidates supported by high-dose inotropes (74% vs 40%; p< 0.001). (C) Cardiac index of candidates supported by low-dose inotropes at the time of listing. The histogram on the left is of cardiac indices for candidates not on inotropes at the time of hemodynamic measurement. The histogram on the right is of cardiac indices of candidates receiving low-dose inotropes at the time of measurement. Candidates to the right of the line would be ineligible for Status 4 listing. For candidates with hemodynamics measured before inotrope initiation, the mean cardiac index was 1.88 liters/min/m2, and the proportion of candidates disqualified by shock criteria was 49%. For candidates with hemodynamics measured on the listed inotrope, the mean cardiac index was 2.21 liters/min/m2, and the proportion disqualified was 46% (p = 0.027 for shock proportion comparison).