Figure 10.

Biplot representation of the principal component analysis of the clinical, infection and inflammation parameters variability. The 16 variables included were: body weight before infection, body temperature at 18 hpi, clinical score at 23 hpi, PBMC and blood neutrophil concentrations at 23 hpi, milk SCC at 18 and 23 hpi, milk CFU concentrations at 18 and 23 hpi, % killing by milk ex vivo at 18 hpi, a-toxin and LukM milk concentrations at 18 hpi, and IFN-γ, IL-17A, TNF-α and IL-8 milk concentrations at 18 hpi. Supplementary variables are the selection groups (CCS+ and CCS−), the infecting S. aureus strains (Ch122 or Ch204), and the severity groups (uncontrolled infection UI or controlled infection CI). Blue dots are the five CI goats, green dots the five UI goats. Analysis was performed with the XLStat software (Spearman correlation, distance biplot).