Table 3.
Effect of decompressive laparotomy on organ function in adults (all patients)
| Variable | No. of studies reporting data of variables | Mean preoperative value | Mean postoperative value | Mean difference following DL | Heterogeneity | Hedges’ g | p Value | ||
|---|---|---|---|---|---|---|---|---|---|
| Cochran’s Q | df | p Value | |||||||
| IAP (mmHg) | 8 | 31.7 ± 6.4 | 13.5 ± 3.0 | − 18.2 ± 6.5 | 56.373 | 7 | < 0.001 | 2.222 | < 0.001 |
| HR (beats/min) | 4 | 122 ± 10.6 | 109 ± 11.6 | − 12.2 ± 9.5 | 7.623 | 3 | 0.054 | 0.505 | 0.040 |
| MAP (mmHg) | 5 | 82 ± 16.3 | 88.8 ± 21.7 | + 6.8 ± 15.7 | 40.398 | 4 | < 0.001 | 0.173 | 0.698 |
| CVP (mmHg) | 6 | 18.6 ± 3.1 | 14 ± 2.9 | − 4.6 ± 2.3 | 13.030 | 5 | 0.023 | 0.624 | 0.022 |
| PCWP (mmHg) | 5 | 23.7 ± 6.7 | 17.9 ± 3.7 | − 5.8 ± 5 | 41.008 | 4 | < 0.001 | 1.117 | 0.029 |
| CI (L/min/m2) | 6 | 4 ± 1.2 | 4.6 ± 1.5 | + 0.82 ± 0.8 | 8.145 | 5 | 0.148 | 0.569 | 0.002 |
| SVRI (dyn·s/cm5·m2) | 3 | 2009.3 ± 364.5 | 1484 ± 451.2 | 311.3 ± 539.4 | 42.86 | 2 | < 0.001 | 0.534 | 0.28 |
| PIP (cmH2O) | 9 | 45.5 ± 8.7 | 35.6 ± 8.0 | − 10.1 ± 3.9 | 22.310 | 8 | 0.004 | 1.344 | < 0.001 |
| PEEP (cmH2O) | 2 | 18.2 ± 13.1 | 17.4 ± 13.2 | − 0.9 ± 0.1 | 0.002 | 1 | 0.966 | 0.078 | 0.768 |
| P/F ratio | 8 | 163.7 ± 48.4 | 234.1 ± 55.8 | + 70.4 ± 49.4 | 11.889 | 7 | 0.104 | 0.894 | < 0.001 |
| UO (ml/h) | 8 | 44.1 ± 30.0 | 139.4 ± 109.4 | + 95.3 ± 105.3 | 23.687 | 7 | 0.001 | 1.061 | < 0.001 |
Abbreviations: IAP Intra-abdominal pressure, HR Heart rate, MAP Mean arterial pressure, CVP Central venous pressure, PCWP Pulmonary capillary wedge pressure, CI Cardiac index, SVRI Systemic vascular resistance index, PIP Peak inspiratory pressure, PEEP Positive end-expiratory pressure, P/F ratio Ratio of partial pressure arterial oxygen and fraction of inspired oxygen, UO Urinary output