Fig. 1. Effects of uranyl acetate on cell viability and LDH leakage in normal rat kidney proximal cells (NRK-52E). After the kidney cells were incubated with different concentrations of uranyl acetate (200, 400 or 800 μM) for 24 h, cell viability (A) was determined by MTT assay, and LDH leakage (B) was tested by a routine colorimetric laboratory method as described in the “Materials and methods” section. Values are expressed as the mean ± SE (n = 5). An asterisk represents a significant difference between uranium-treated and untreated cells (one-way ANOVA, *P < 0.05, **P < 0.01, ***P < 0.001).
