Table 1. Intracellular ROS, MDA and oxidative stress parameters in normal rat kidney proximal cells (NRK-52E) intoxicated by uranyl acetate (U).
Parameters | Control | U (200 μM) | U (400 μM) | U (800 μM) |
ROS (100%) | 100 ± 3.21 | 122 ± 0.78* | 156 ± 2.33** | 321 ± 0.75*** |
MDA (nmol per mg prot) | 9.18 ± 0.03 | 24.23 ± 0.31* | 31.72 ± 0.04** | 40.32 ± 0.27** |
GSH (nmol per mg prot) | 22.56 ± 0.76 | 18.07 ± 0.67* | 16.54 ± 0.78* | 11.23 ± 0.39** |
SOD (unit per mg prot) | 1.27 ± 0.51 | 0.95 ± 0.71* | 0.81 ± 0.91** | 0.64 ± 0.37** |
CAT (unit per mg prot) | 4.60 ± 0.27 | 3.81 ± 0.57* | 2.67 ± 0.83** | 1.21 ± 0.61*** |