Table 5. Levels of cytokines and CRP stratified by DEE exposure duration (median, 5–95%).

Indicator	Controls (n = 108)	Exposure duration (years)			P trend #
		<5 (n = 33)	5–10 (n = 83)	>10 (n = 21)
IL-1β (pg ml–1)	3.29 (0.21–16.73)	1.18 (0.16–7.86)*	1.18 (0.04–11.43)*	2.54 (0.04–15.01)	0.43
IL-6 (pg ml–1)	27.59 (1.70–141.04)	20.58 (1.45–79.97)	16.47 (0.80–67.06)*	13.81 (0.58–66.78)*	0.006
IL-8 (pg ml–1)	608.60 (157.18–1725.36)	468.55 (0.60–1663.90)*	414.11 (0.60–1062.81)*	373.80 (234.41–1077.12)	0.078
MIP-1β (pg ml–1)	821.03 (235.40–2810.92)	663.12 (248.50–1481.72)	512.69 (0.40–2042.21)*	854.70 (230.97–2865.27)	0.54
TNF-α (pg ml–1)	78.43 (0.60–195.90)	97.22 (18.30–188.22)	60.08 (0.60–165.38)	73.67 (17.05–180.32)	0.70
MCP-1 (pg ml–1)	225.95 (70.12–420.64)	192.54 (78.02–457.75)	214.64 (0.65–411.95)*	265.02 (124.95–451.38)	0.74
CRP (mg L–1)	0.10 (0.07–4.48)	0.50 (0.07–3.60)	0.80 (0.07–5.64)*	0.80 (0.07–3.73)*	0.026