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Based on a computational analysis, STAT3 is identified as a virtual target of microRNA (miR)-125b, and the potential binding sites were located in the 3′UTR of STAT3. (A) STAT3 was identified as the candidate target gene of microRNA (miR)-125b with the ‘seed sequence’ in the 3′UTR of STAT3. (B) Long intergenic non-coding RNA (lincRNA) of the NED25 gene inhibited luciferase activity of wild-type STAT3 3′UTR. (C) miR-125b inhibited luciferase activity of wild-type STAT3 3′UTR.
