Table 1. Comparison of a 48 h and 72 h recovery period for the micronucleus assay following treatment of three dimensional spheroids of MCF-7 cells with increasing doses of benzo[a]pyrene (BaP).
Concentration of BaP | Number of micronuclei per 1000 cells |
|
48 h recovery | 72 h recovery | |
DMSO | 3.5 | 17.8 |
10–10 M | 11.2 | 18.5 |
10–9 M | 10.5 | 17.8 |
10–8 M | 13.0 | 17.8 |
10–7 M | 16.3 | 16.0 |
10–6 M | 19.7 | 23.5 |
10–5 M | 26.0 | 31.3 |