Fig. 1. Schematic illustration of glomerular endothelial barrier formation on a chip. (a) Illustration of Cd exposure in daily life. (b) Schematic design of the microfluidic chip for renal toxicity testing. The microfluidic device consists of a cell culture channel, a gel channel and a collection channel, in which the GECs are cultured on the gel-coated surface to form the glomerular endothelial barrier. (c) Photo of the real microfluidic device. (d) Illustration of glomerular structure.
