Table 3.
Information of between-group vertex-wise analyses and whole group vertex-wise correlation analyses
| Cluster size (mm2) | Peak t-value | MNI coordinates peak value (x, y, z) | Anatomical location | P-value | |
|---|---|---|---|---|---|
| Right cortical thickness | |||||
| Cluster group effect | 537.38 | 4.347 | 34.0, −11.1, 16.3 | Insula / transverse temporal / superior temporal / supramarginal / precentral | 0.024 |
| Cluster T2DM lower than controls | 571.43 | 4.720 | 34.1, −10.3, 16.1 | Insula / transverse temporal / superior temporal / supramarginal / precentral | 0.017 |
| Cluster obese lower than controls | 556.05 | 3.380 | 37.9, −34.4, 12.5 | Insula / transverse temporal / superior temporal / supramarginal / precentral / pars opercularis | 0.019 |
| Left surface area | |||||
| Cluster group effect | 678.51 | 2.892 | −12.7, −95.2, 20.0 | Lateral occipital / superior parietal / cuneus | 0.063 |
| Cluster T2DM lower than controls | 972.56 | 3.478 | −13.3, −94.9, 20.3 | Lateral occipital / superior parietal / cuneus | 0.007 |
| Cluster T2DM lower than obese | 748.11 | 4.890 | −6.9, −19.6, 67.0 | Paracentral | 0.040 |
| Whole group insulin | |||||
| Cluster 1 left area negative | 2008.94 | −4.278 | −23.6, 49.2, 9.6 | Rostral middle frontal / superior frontal | 0.0002 |
| Cluster 2 left area negative | 1373.58 | −2.697 | −64.1, −31.9, 8.5 | Superior temporal / supramarginal / banks of the superior temporal sulcus | 0.0008 |
| Cluster 1 left volume negative | 951.04 | −2.831 | −58.7, −51.3, 22.2 | Superior temporal / supramarginal / banks of the superior temporal sulcus | 0.001 |
| Cluster 2 left volume negative | 599.10 | −3.057 | −35.9, −17.2, 7.4 | Insula / transverse temporal | 0.020 |
| Cluster 1 left thickness positive | 491.43 | 4.212 | −7.3, 35.2, −22.7 | Medial orbitofrontal / lateral orbitofrontal | 0.040 |