Table 3.

Comparison of cytokine levels between pSS patients and controls

	Cases pg/ml, median (IQR) n = 51	Controls, pg/ml, median (IQR) n = 33	p value+
IL-1β	0 (0; 0)	0 (0; 0)	0.92
IL-2	0 (0; 25.0)	0 (0; 24.4)	0.86
IL-3	0 (0; 67.8)	0 (0; 88.7)	0.84
IL-4	0 (0; 0)	0 (0; 0)	0.20
IL-6	25.2 (14.0; 30.9)	15.3 (10.6; 22.0)	0.003**
IL-8	19.9 (15.9; 22.8)	16.7 (14.1; 20.8)	0.06
IL-10	0 (0; 0)	0 (0; 0)	0.18
IL-12	7.4 (0; 10.8)	0 (0; 8.3)	0.02*
IL-17	0 (0; 51.2)	0 (0; 0)	0.002**
IL-18	294 (187.7; 500.3)	214.5 (119.0; 297.5)	0.008**
IL-33	11.2 (0; 16.1)	12.5 (0; 17.7)	0.62
IFN-α	0 (0; 0)	0 (0; 0)	0.53
IFN- γ	0 (0; 1.3)	0 (0; 1.0)	0.43
TNF-α	12.1 (5.7; 16.9)	8.5 (5.9; 11.5)	0.14
BAFF	265.6 (182.4; 376.2)	276.1 (142.9; 391.6)	0.79
EGF	139.8 (60.0; 227.1)	136.4 (93.2; 177.3)	0.89
Fas ligand	9.5 (7.2; 15.3)	11.4 (6.9; 15.2)	0.48
RANTES	15673.7 (11374.1; 25397.6)	17073.0 (13345.9; 20037.8)	0.56
TGF-β1	22.4 (6.7; 35.6)	12.7 (9.2; 36.6)	0.75

*p < 0.05

**p < 0.01

⁺Mann–Whitney U test