Table 4.

Comparison of cytokine levels between never smoking and ever smoking pSS patients

	Ever smokers (pSS) n = 24 pg/ml, median (IQR)	Never smokers (pSS) n = 27 pg/ml, median (IQR)	p value+
IL-1β	0 (0; 0)	0 (0; 0)	0.30
IL-2	0 (0; 28.4)	0 (0; 19.2)	0.85
IL-3	0 (0; 0)	0 (0; 96.9)	0.36
IL-4	0 (0; 0)	0 (0; 0)	1.0
IL-6	25.0 (14.4; 29.4)	25.2 (13.0; 36.7)	0.94
IL-8	21.8 (15.9; 24.1)	18.3 (15.5; 21.4)	0.18
IL-10	0 (0; 0)	0 (0; 39.3)	0.74
IL-12	9.7 (5.6; 12.9)	7.1 (0; 9.8)	0.20
IL-17	0 (0; 75.7)	39.0 (0; 46.6)	0.86
IL-18	364.3 (250.4; 659.3)	234.5 (166.3; 500.3)	0.06
IL-33	11.2 (0; 19.3)	11.2 (0; 15.6)	0.95
IFN-α	0 (0; 0)	0 (0; 0)	0.51
IFN-γ	0.7 (0; 1.3)	0 (0; 1.0)	0.58
TNF-α	13.8 (7.2; 20.8)	7.5 (4.9; 15.9)	0.03*
BAFF	256.1 (191.9; 375.2)	265.6 (156.7; 388.3)	0.95
EGF	154.8 (55.4; 252.0)	133.9 (70.8; 202.8)	0.53
FAS ligand	10.3 (7.3; 16.6)	9.2 (6.5; 12.6)	0.50
RANTES	17051.1 (11883.2; 27559.6)	15443.0 (9730.2; 19827.9)	0.46
TGF-β1	21.2 (4.2; 26.9)	22.4 (9.3; 55.0)	0.14

*p < 0.05

⁺Mann–Whitney U test