Table 3.
(Comparison of medians) TNF-α −1031T/C genotype distribution according to both clinical–demographic and nutritional factors of studied patients
| Factor (median ± SD) | CC | CT | TT | p | CT and CC | TT | p |
|---|---|---|---|---|---|---|---|
| TNF-α −1031T/C | |||||||
| Weight (kg) (I) all patients | 55 ± 11.64 | 60 ± 7.07 | 64 ± 9.01 | 0.042 | 58 ± 7.83 | 64 ± 9.01 | 0.044 |
| Weight (kg) (I) men | 61 ± 8.21 | 63 ± 7.43 | 69 ± 10.99 | 0.049 | 61 ± 7.06 | 69 ± 10.99 | 0.012 |
| Weight (kg) (I) women | 53 ± 8.72 | 55 ± 9.52 | 62.5 ± 9.65 | 0.133 | 53.5 ± 8.24 | 62.5 ± 9.65 | 0.045 |
| Weight (kg) (VII) all patients | 51 ± 10.23 | 58 ± 8.67 | 60 ± 9.76 | 0.389 | 58 ± 9.02 | 60 ± 9.76 | 0.322 |
| Weight (kg) (VII) men | 60 ± 4.35 | 58 ± 8.85 | 60 ± 9.73 | 0.381 | 58.5 ± 8.22 | 60 ± 9.73 | 0.350 |
| Weight (kg) (VII) women | 51 ± 5.77 | 66 ± 8.49 | 55 ± 10.03 | 0.090 | 51 ± 11.64 | 55 ± 10.03 | 0.840 |
| BMI (I) all patients | 19.95 ± 4.49 | 22.83 ± 4.59 | 23.54 ± 4.07 | 0.122 | 22.71 ± 4.74 | 23.54 ± 4.07 | 0.179 |
| BMI (I) men | 23.09 ± 2.08 | 22.58 ± 4.19 | 24.09 ± 4.40 | 0.464 | 22.84 ± 3.97 | 24.09 ± 4.40 | 0.429 |
| BMI (I) women | 17.96 ± 3.73 | 20.85 ± 3.23 | 21.43 ± 3.73 | 0.186 | 19.95 ± 7.45 | 21.43 ± 3.73 | 0.093 |
| BMI (VII) all patients | 20.22 ± 4.95 | 19.53 ± 4.18 | 19.37 ± 3.67 | 0.866 | 19.53 ± 4.29 | 19.37 ± 3.67 | 0.908 |
| BMI (VII) men | 22.53 ± 3.05 | 19.53 ± 3.58 | 21.05 ± 3.81 | 0.343 | 20.07 ± 3.63 | 21.05 ± 3.81 | 0.860 |
| BMI (VII) women | 16.65 ± 2.91 | 18.81 ± 0.76 | 19.00 ± 3.76 | 0.348 | 18.52 ± 2.46 | 19.00 ± 3.76 | 0.315 |
| Transferrin (g/L) | 2.80 ± 0.47 | 2.50 ± 0.61 | 2.50 ± 0.60 | 0.279 | 2.60 ± 0.59 | 2.50 ± 0.60 | 0.421 |
| Prealbumin (g/dL) | 0.3 ± 0.05 | 0.2 ± 0.08 | 0.2 ± 0.08 | 0.355 | 0.25 ± 0.08 | 0.2 ± 0.08 | 0.178 |
| TP (g/L) (I) | 6.64 ± 0.53 | 6.73 ± 0.48 | 6.71 ± 0.55 | 0.985 | 6.73 ± 0.48 | 6.71 ± 0.55 | 0.943 |
| TP (g/L) (VII) | 5.83 ± 0.66 | 6.36 ± 0.59 | 6.46 ± 0.60 | 0.036 | 6.26 ± 0.56 | 6.46 ± 0.60 | 0.048 |
| Albumin (g/L) (I) | 3.19 ± 0.13 | 3.26 ± 0.20 | 3.38 ± 0.24 | 0.048 | 3.23 ± 0.19 | 3.38 ± 0.24 | 0.047 |
| Albumin (g/L) (VII) | 2.98 ± 0.62 | 3.11 ± 0.44 | 3.28 ± 0.38 | 0.031 | 3.04 ± 0.16 | 3.28 ± 0.38 | 0.013 |
| TNF-α plasma level (pg/mL) | 10.70 ± 0.72 | 9.76 ± 1.54 | 9.08 ± 1.49 | 0.006 | 9.98 ± 1.37 | 9.08 ± 1.49 | 0.0015 |
I Measurement conducted before the commencement of therapy, VII measurement conducted after the termination of therapy