Table 4.
(Comparison of means) TNF-α −1031T/C genotype distribution according to both clinical–demographic and nutritional factors of studied patients
| Factor (mean ± SD) | CC | CT | TT | p | CT and CC | TT | p |
|---|---|---|---|---|---|---|---|
| TNF-α −1031T/C | |||||||
| Weight (kg) (I) all patients | 54.65 ± 11.51 | 62.43 ± 11.29 | 66.22 ± 11.65 | 0.043 | 60.72 ± 11.32 | 66.22 ± 11.65 | 0.042 |
| Weight (kg) (I) men | 62.0 ± 10.0 | 63.76 ± 11.29 | 67.87 ± 11.65 | 0.238 | 63.65 ± 11.21 | 67.87 ± 11.65 | 0.198 |
| Weight (kg) (I) women | 49 ± 11.51 | 62.67 ± 10.69 | 75 ± 11.28 | 0.043 | 58.11 ± 11.03 | 75 ± 11.28 | 0.049 |
| Weight (kg) (VII) all patients | 55.67 ± 9.96 | 59.16 ± 9.54 | 60.54 ± 9.51 | 0.624 | 57.56 ± 9.54 | 60.54 ± 9.51 | 0.424 |
| Weight (kg) (VII) men | 60 ± 10 | 58.35 ± 11.29 | 61.20 ± 11.60 | 0.514 | 58.95 ± 9.54 | 61.20 ± 11.60 | 0.409 |
| Weight (kg) (VII) women | 47.67 ± 9.97 | 65.0 ± 9.35 | 57.17 ± 9.81 | 0.148 | 54.6 ± 9.42 | 57.17 ± 9.81 | 0.694 |
| BMI (I) all patients | 19.58 ± 4.42 | 23.28 ± 4.28 | 23.52 ± 4.45 | 0.125 | 22.40 ± 4.28 | 23.52 ± 4.45 | 0.336 |
| BMI (I) men | 22.28 ± 4.31 | 22.76 ± 4.28 | 24.08 ± 4.47 | 0.492 | 22.69 ± 4.28 | 24.08 ± 4.47 | 0.237 |
| BMI (I) women | 16.88 ± 4.42 | 22.85 ± 4.07 | 25.43 ± 4.33 | 0.043 | 19.28 ± 4.37 | 25.43 ± 4.33 | 0.250 |
| BMI (VII) all patients | 20.22 ± 3.96 | 20.66 ± 3.91 | 20.05 ± 3.91 | 0.851 | 20.55 ± 3.91 | 20.05 ± 3.91 | 0.609 |
| BMI (VII) men | 23.03 ± 4.31 | 20.79 ± 3.91 | 21.20 ± 3.91 | 0.369 | 21.29 ± 3.91 | 21.20 ± 3.91 | 0.920 |
| BMI (VII) women | 16.41 ± 3.96 | 19.84 ± 3.87 | 20.12 ± 3.96 | 0.134 | 17.78 ± 3.98 | 20.12 ± 3.96 | 0.100 |
| Transferrin (g/L) | 2.78 ± 0.40 | 2.58 ± 0.60 | 2.45 ± 0.59 | 0.255 | 2.58 ± 0.60 | 2.45 ± 0.59 | 0.400 |
| Prealbumin (g/dL) | 0.283 ± 0.09 | 0.253 ± 0.08 | 0.231 ± 0.08 | 0.262 | 0.261 ± 0.08 | 0.231 ± 0.08 | 0.945 |
| TP (g/L) (I) | 6.67 ± 0.51 | 6.68 ± 0.50 | 6.70 ± 0.52 | 0.985 | 6.68 ± 0.50 | 6.70 ± 0.52 | 0.866 |
| TP (g/L) (VII) | 5.69 ± 0.72 | 6.40 ± 0.66 | 6.53 ± 0.65 | 0.002 | 6.18 ± 0.66 | 6.53 ± 0.65 | 0.150 |
| Albumin (g/L) (I) | 3.19 ± 0.22 | 3.32 ± 0.24 | 3.46 ± 0.24 | 0.014 | 3.29 ± 0.24 | 3.46 ± 0.24 | 0.008 |
| Albumin (g/L) (VII) | 2.87 ± 0.43 | 3.09 ± 0.39 | 3.25 ± 0.40 | 0.044 | 3.06 ± 0.39 | 3.25 ± 0.40 | 0.040 |
| TNF-α plasma level (pg/mL) | 10.83 ± 1.34 | 9.67 ± 1.60 | 9.31 ± 1.57 | 0.002 | 10.71 ± 1.60 | 9.31 ± 1.57 | < 0.001 |
I measurement conducted before the commencement of therapy, VII measurement conducted after the termination of therapy