Table 6.
Factors affecting the overall survival of HNC patients in log-rank test and multivariate Cox logistic regression
| Factor | Log-rank test | |
|---|---|---|
| HR [95% CI] | p | |
| Gender | 1.171 [0.368–3.723] | 0.777 |
| Age | 1.132 [0.452–2.837] | 0.792 |
| Smoking history | 1.715 [0.515–5.712] | 0.460 |
| Alcohol consumption | 1.301 [0.531–3.226] | 0.550 |
| Performance status | 3.361 [0.60-18.831] | 0.019 |
| Tumor stage | 1.881 [0.676–5.239] | 0.303 |
| Parenteral nutrition | 1.617 [0.548–4.772] | 0.322 |
| SGA | 2.818 [0.996–7.972] | 0.126 |
| NRS | 1.890 [0.644–5.543] | 0.271 |
| BMI loss > 5% (I vs VII) | 1.752 [0.695–4.415] | 0.270 |
| BMI loss > 10% (I vs VII) | 1.436 [0.578–3.520] | 0.443 |
| Weight loss > 5% (I vs VII) | 1.217 [0.489–3.032] | 0.673 |
| Weight loss > 10% (I vs VII) | 1.374 [0.556–3.396] | 0.492 |
| Total protein (I) | 1.227 [0.499–3.020] | 0.653 |
| Albumin (I) | 1.726 [0.698–4.267] | 0.228 |
| TNF-α −1031T/C | 4.960 [0.808–30.48] | 0.019 |
| Plasma TNF-α | 2.582 [1.031–6.468] | 0.028 |
| Cox proportional-hazard regression model | ||
| Performance status | 3.10 [0.930–10.31] | 0.047 |
| TNF-α −1031T/C | 2.142 [1.124–4.08] | 0.021 |
| Overall model fit p = 0.011, stepwise method | ||
I Measurement conducted before the commencement of therapy, VII measurement conducted after the termination of therapy