Table 1.
Patient demographic characteristics. Staphylococcus aureus bacteraemia before (2011–2012) and after a protocol adherence intervention (2014–2015)
| Variable | Pre-intervention (n = 98) | Post-intervention group (n = 85) | p value |
|---|---|---|---|
| Age, median years (min, max) | 69, 65 (19, 94) | 76.49 (35, 98) | 0.016 |
| Female sex | 47 (48%) | 35 (41%) | 0.44 |
| Classification SAB | |||
| Uncomplicated SAB | 11 (11%) | 15 (18%) | 0.303 |
| Complicated SAB | 87 (89%) | 70 (82%) | |
| Risk factors | |||
| Community acquisition | 63 (64%) | 55 (65%) | |
| Diabetes mellitus | 28 (29%) | 26 (31%) | |
| Positive follow-up blood cultures 48/72 h | 13 (13%) | 21 (25%) | |
| Prosthetic material | 31 (32%) | 29 (34%) | |
| Persistent fever after 72 h | 4 (4%) | 9 (11%) | |
| Catheter-related and in situ | 3 (3%) | 2 (2%) | |
| Immunocompromised | 12 (12%) | 9 (11%) | |
| Metastatic infections | 23 (23%) | 23 (27%) | |
| Purulent thrombophlebitis | 11 (11%) | 0 (0%) | |
| Malignancy | 18 (18%) | 10 (12%) | |
| Alcohol | 10 (10%) | 7 (8%) | |
| Haemodialysis | 3 (3%) | 1 (1%) | |
| No. of risk factors | |||
| 0 | 11 (11%) | 15 (18%) | 0.590 |
| 1 | 27 (28%) | 16 (19%) | |
| 2 | 31 (32%) | 28 (33%) | |
| 3 | 22 (22%) | 16 (19%) | |
| 4 | 5 (5%) | 6 (7%) | |
| 5 | 3 (3%) | 4 (5%) | |
| Source of infection | |||
| Health care-related | 50 (51%) | 37 (44%) | |
| Surgery | 11 (22%) | 6 (16%) | |
| Urinary tract/CAD | 6 (12%) | 8 (22%) | |
| CVC/PAC | 11 (22%) | 5 (14%) | |
| Peripheral catheter | 12 (24%) | 11 (30%) | |
| Unknown source | 26 (52%) | 21 (57%) | |
Patient demographics. SAB, Staphylococcus aureus bacteraemia; CAD, urine catheter; CVC, central venous catheter; PAC, port a cath; NS, not significant. A p value < 0.05 is considered statistically significant