Table 3.
Point prevalence of systemic sclerosis in 2013 (per million people)
| Cases | Denominator | Crude prevalence | Crude odds ratios (95% CI) | Adjusted Odds ratios (95% CI) | P value1 | |
|---|---|---|---|---|---|---|
| Overall | 1337 | 4,362,809 | 307 (290–323) | |||
| Sex | ||||||
| Male | 227 | 2,155,960 | 105 (92–120) | 1 | 1 | P < 0.0001 |
| Female | 1110 | 2,206,814 | 503 (474–533) | 4.8 (4.1–5.5) | 4.6 (3.9–5.2) | |
| Age group (years) | ||||||
| Age 0–15 | 13 | 781,568 | 17 (9–28) | 0.2 (0.1–0.4) | 0.2 (0.1–0.4) | Ptrend < 0.0001 |
| Age 16–39 | 111 | 1,322,291 | 84 (69–101) | 1 | 1 | |
| Age 40–54 | 283 | 959,587 | 295 (262–331) | 3.5 (2.8–4.4) | 3.5 (2.8–4.4) | |
| Age 55–69 | 505 | 754,643 | 669 (612–730) | 8.0 (6.5–9.8) | 7.9 (6.5–9.8) | |
| Age 70–84 | 362 | 433,661 | 835 (751–925) | 10.0 (8.0–12.3) | 9.4 (7.6–11.7) | |
| Age 85+ | 63 | 111,059 | 567 (436–726) | 6.8 (5.0–9.2) | 5.6 (4.1–7.7) | |
| IMD 2010 | ||||||
| Quintile 1 | 188 | 600,110 | 313 (270–361) | 1 | 1 | Ptrend = 0.68 |
| Quintile 2 | 188 | 598,616 | 314 (271–362) | 1.0 (0.8–1.2) | 1.0 (0.8–1.2) | |
| Quintile 3 | 147 | 519,240 | 283 (239–333) | 0.9 (0.7–1.1) | 0.9 (0.8–1.2) | |
| Quintile 4 | 145 | 520,410 | 279 (235–328) | 0.9 (0.7–1.1) | 1.0 (0.8–1.3) | |
| Quintile 5 | 110 | 424,476 | 259 (213–312) | 0.8 (0.7–1.0) | 1.1 (0.8–1.3) | |
| IMD not known | 559 | 1,699,957 | 329 (302–357) | 1.0 (0.9–1.2) | 1.1 (0.9–1.3) | |
Crude odds ratio is calculated using univariable logistic regression, and adjusted odds ratio is calculated using multi-variable logistic regression including sex, age group, and IMD-quintile as a priori confounders
aFrom multi-variable (adjusted) analysis using the likelihood ratio test