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. 2018 Feb 17;75(16):3039–3050. doi: 10.1007/s00018-018-2778-z

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© The Author(s) 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 5 — Summary of intra- and extra-islet peptide/GPCR signalling pathways in human islets (a) and in ICR (b) and C57 (c) mouse islets. Data are presented as % of the pathways that occur within islets (intra-islet), where the ligands are released from islets to act at non-islet GPCRs (extra-islet), or where the peptide ligands have been proposed to interact with as yet unidentified GPCRs (undefined)