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Effect of BIBO 3304 trifluoroacetate on insulin (a, d), glucagon (b, e) and somatostatin (c, f) secretion from mouse (a–c) and human (d–f) islets. Data are shown as mean + SEM insulin, glucagon and somatostatin release per islet per hour in static incubations, n = 8 for all hormones in both mouse and human islets. *p < 0.05, **p < 0.01; ***p < 0.001
