Table 1.
Baseline characteristics of participants (n = 312)
| High exposure No. (%) | Low exposure No. (%) | P* | |
|---|---|---|---|
| Age, y | |||
| Mean±SD | 58.5±12.6 | 56.5±12.9 | .18 |
| Sex | |||
| Male | 94 (56.6) | 81 (55.5) | .84 |
| Female | 72 (43.4) | 65 (44.5) | |
| Tumor location | .21 | ||
| Rectum | 81 (48.8) | 61 (41.8) | |
| Colon | 85 (51.2) | 85 (58.2) | |
| TNM stage | .008 | ||
| II | 92 (55.4) | 59 (40.4) | |
| III | 74 (44.6) | 87 (59.6) | |
| Chemotherapy regimen | |||
| 5-Fu+DDP | 0 | 1 (0.7) | .004 |
| FOLFIRI | 1 (0.6) | 0 | |
| FOLFOX | 76 (45.8) | 48 (32.9) | |
| Mayo Clinic | 0 | 1 (0.7) | |
| XELODA | 7 (4.2) | 3 (2.1) | |
| XELOX | 14 (8.4) | 5 (3.4) | |
| 5-fu+CF+LOHP | 9 (5.4) | 7 (4.8) | |
| Unknown | 3 (1.8) | 1 (0.7) | |
| None | 56 (33.7) | 80 (54.8) | |
| Stage and chemotherapy | <.001 | ||
| II with chemo | 51 (30.7) | 29 (19.9) | |
| II without chemo | 41 (24.7) | 30 (20.5) | |
| III with chemo | 59 (35.5) | 37 (25.3) | |
| III without chemo | 15 (9.0) | 50 (34.2) |
*
Chi-square test or Fisher’s exact test for categorical variables; t test for continuous variables.