Table 3.

Change in plasma oxalate concentration from baseline to week 24

	Plasma oxalate (μmol/L)
	OC3		Placebo
	Absolute values	% change to baseline	Absolute values	% change to baseline
Baselinea
n	21	–	13	–
Mean (SD)	13.92 (7.578)	–	9.68 (4.024)	–
Median	11.00	–	8.90	–
Min, Max	7.3, 35.0	–	4.5, 18.5	–
Week 24a
n	21	21	13	13
Mean (SD)	12.38 (7.79)	−12.20 (22.55)	9.82 (6.877)	5.23 (68.53)
Median	9.00	−14.42	6.70	−8.45
Min, Max	3.3, 35.0	−64.5, 30.3	3.0, 24.1	−60.3, 192.3
Mean treatment difference	–	−17.43	–	–
95% confidence interval	–	−50.21, 15.34	–	–
p valueb	–	0.75	–	–

SD standard deviation

^a Numbers were derived from a post hoc analysis after the finalisation of the Clinical Study Report (CSR)

^b p value was derived after a Wilcoxon-Mann–Whitney-test