Table 1.
Mixed infection |
Single infection |
||||
---|---|---|---|---|---|
R parasites | S parasites | n | R parasites | n | |
No drugs | 106 | 106 | 5a | 106 | 5 |
105 | 106 | 5b | 105 | 5 | |
103 | 106 | 5 | 103 | 5 | |
101 | 106 | 10a,b | 101 | 10 | |
Drugs | 106 | 106 | 5 | 106 | 5 |
105 | 106 | 5a | 105 | 5 | |
103 | 106 | 5a,b | 103 | 5 | |
101 | 106 | 10 | 101 | 10a,a |
Groups were inoculated with clone R in the single infections, or clone R and clone S for the mixed infections. The inoculum of clone S was always 106 parasites, the inoculum of clone R varied from 106 to 101 parasites. All treatment groups with an inoculum size of 101 parasites had 10 mice at the start of the experiment. All other treatment groups consisted of 5 mice. Drug treatment was given on Days 6–9 post-infection.
An excluded mouse.
A dead or euthanized mouse.