Fig. 5. Effect of eriodictyol treatment with DMH-induced rats in hepatic tissue. (A) Normal histological appearance of the liver (Group 1). (B) Showing micro and macrovesicular types of fatty changes, Kupffer cell hyperplasia, nuclear pleomorphism and inflammatory cell infiltrates in the portal triad. (C) Positive control rats group showing normal crypts, initiation, post-initiation and entire-period (D, E and F) treatment in DMH-induced rat livers showing less neoplastic cells, a near-normal architecture and significant improvement in liver histopathology.