Table 9. Effect of eriodictyol on colonic tissue levels of SOD and CAT in control and experimental rats.
Parameters and samples | Groups |
|||||
Control | DMH | Eriodictyol | Initiation | Post-initiation | Entire period | |
SOD a | ||||||
Proximal colon | 10.23 ± 0.11a | 5.42 ± 0.03b | 11.12 ± 0.04a | 7.52 ± 0.12c | 7.85 ± 0.34c | 8.74 ± 0.18d |
Distal colon | 10.61 ± 0.21a | 5.49 ± 0.08b | 11.19 ± 0.13c | 7.51 ± 0.05d | 7.95 ± 0.11d | 8.77 ± 0.36e |
Intestine | 10.20 ± 0.14a | 5.39 ± 0.17b | 11.09 ± 0.22c | 7.49 ± 0.27d | 7.84 ± 0.24d | 8.71 ± 0.05e |
CAT b | ||||||
Proximal colon | 38.35 ± 0.14a | 22.42 ± 0.33b | 39.12 ± 0.18a | 28.33 ± 0.01c | 29.16 ± 0.11c | 30.91 ± 0.13d |
Distal colon | 38.21 ± 0.45a | 22.84 ± 0.08b | 40.42 ± 0.34c | 28.57 ± 0.04d | 29.49 ± 0.06d | 31.31 ± 0.61e |
Intestine | 37.81 ± 0.34a | 21.89 ± 0.63b | 39.14 ± 0.64c | 28.08 ± 0.17d | 28.61 ± 0.42d | 29.62 ± 0.37c,d |
aEnzyme required for 50% inhibition of NBT reduction per min per mg of protein.
bμmoles of H2O2 utilized per mg protein.