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. 2017 May 18;6(5):654–663. doi: 10.1039/c7tx00065k

Table 3. mRNA and protein levels of CYP1A1 and 1A2 and activities of CYP450s and GSTs in rat lungs treated with PM2.5 or 9-NA.

Groups CYP1A1 mRNA (changed fold) CYP1A1 protein (ng mg–1 protein) CYP1A2 mRNA (changed fold) CYP1A1 protein (ng mg–1 protein) GST (U mg–1 protein) CYP450 (U mg–1 protein)
Control 1.00 ± 0.26 22.7 ± 3.9 1.00 ± 0.32 2 ± 0.14 26.1 ± 2.5 0.071 ± 0.008
PM2.5 1.44 ± 0.25* 29.7 ± 4* 1.31 ± 0.29 2.61 ± 0.3** 34.8 ± 4.3** 0.103 ± 0.016*
9-NA-1 1.25 ± 0.27 25.5 ± 4.4 1.16 ± 0.31 2.17 ± 0.2 29 ± 3 0.079 ± 0.013
9-NA-2 1.47 ± 0.37* 27.4 ± 4.2 1.38 ± 0.34 2.23 ± 0.28 32.4 ± 3** 0.086 ± 0.01
9-NA-3 1.59 ± 0.46* 31.1 ± 4.9* 1.44 ± 0.32* 2.68 ± 0.21** 36.5 ± 3.3** 0.12 ± 0.037**