Fig. 4. Epigenetic profiling of Pdx1 at 8 weeks of age. (A) The abundance of AceH3, AceH4, H3K4me3, and H3K9me2 at the Pdx1 promoter. Data are represented as percent of input control, which went through the analyses exactly as the test samples except for the IP step (n = 3). (B) DNA methylation status at the Pdx1 promoter (n = 3). Data are represented as mean ± SEM. *p < 0.05, ***p < 0.001 by two-tailed Student's t-test.