Table 5. Correlations between TP53 mutational status and clinicopathological parameters.
| Characteristics | Total number (%) | TP53 mutant |
TP53 wild-type |
P-value | ||
|---|---|---|---|---|---|---|
| Age, year | ≤ 65 years | 18(41) | 12(67) | 6(33) | 0.08 | |
| > 65 years | 26(59) | 23(89) | 3(11) | |||
| Gender | Male | 37(84) | 29(78) | 8(22) | 0.55 | |
| Female | 7(16) | 6(86) | 1(14) | |||
| Tumor type | NSCLC | ADC | 13(30) | 10(77) | 3(23) | 0.13 |
| SCC | 24(55) | 18(75) | 6(25) | |||
| LCC | 3(7) | 3(100) | 0(0) | |||
| LCC/SCC | 1(2) | 1(100) | 0(0) | |||
| NM | 2(4) | 2(100) | 0(0) | |||
| SCLC | SCLC | 1(2) | 1(100) | 0(0) | ||
| Histological Grade | ADC | Well | 2(22) | 1(50) | 1(50) | 0.56 |
| Moderate | 4(45) | 3(75) | 1(25) | |||
| Poor | 3(33) | 2(67) | 1(33) | |||
| SCC | Well | 9(43) | 6(67) | 3(33) | 0.49 | |
| Moderate | 5(24) | 5(100) | 0(0) | |||
| Poor | 7(33) | 5(71) | 2(29) | |||
| Inflammation (SCC) | Yes | 0(0) | 6(67) | 3(33) | 0.54 | |
| No | 0(0) | 4(80) | 1(20) | |||
NSCLC = non-small cell lung cancer, SCLC = small cell lung cancer, ADC = adenocarcinoma, SCC = squamous cell carcinoma, LCC = large cell carcinoma.
NM = not mention.