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. Author manuscript; available in PMC: 2019 Jun 20.
Published in final edited form as: ACS Chem Neurosci. 2018 Apr 6;9(6):1327–1337. doi: 10.1021/acschemneuro.7b00510

Figure 5. L-SPD inhibits cue-induced reinstatement of sucrose-seeking.

Figure 5.

Data for extinction (EXT) training was based on average performance across the last 3 sessions. Vehicle-treated rats showed a significant increase in active lever presses during cue-induced reinstatement (RST) relative to EXT (p < 0.001; within-group comparison) (a). L-SPD (10 mg/kg) significantly reduced active lever presses during RST when compared to vehicle (p < 0.001; between-group comparison) (a). There were no significant differences within or between treatment groups in terms of inactive lever presses across EXT and RST (b). Data are shown as mean + S.E.M. (n = 7–8 per group). +++p < 0.001 relative to EXT (within-group comparison); ***p < 0.001 relative to vehicle (VEH) (between-group comparison).