Table 2. Mean levels of 3-(2-deoxy-β-d-erythro-pentafuranosyl)pyrimido[1,2-α]purin-10(3H)-one deoxyguanosine (M1dG) adducts per 108 normal nucleotides in the nasal epithelia of workers occupationally exposed to formaldehyde compared to the controls, and according to study variables.
| Nasal epithelia M1dG adducts | |||
| N | Mean levels ± SE | P-values a | |
| Age | |||
| <42 years b | 31 | 90 ± 15 | |
| 42–49 years | 35 | 87 ± 16 | 0.841 |
| >49 years | 29 | 68 ± 10 | 0.492 |
| P-value for trend | 0.348 | ||
| Tobacco smoking | |||
| Non-smokers b | 57 | 82.4 ± 11 | |
| Smokers | 38 | 82.0 ± 12 | 0.637 |
| Jobs | |||
| Controls b | 45 | 49.6 ± 3.4 | |
| Plastic laminate plant workers | 50 | 111.6 ± 14.3 | <0.001 |
| Personal formaldehyde exposure | |||
| <25 b μg m–3 | 23 | 47.6 ± 4.4 | |
| 25–66 μg m–3 | 19 | 59.2 ± 11.6 | 0.703 |
| >66 μg m–3 | 53 | 105.5 ± 13.4 | 0.001 |
| P-value for trend | 0.002 | ||
a P-values after adjusting for confounding factors.
bReference level.