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. 2018 May 18;7(4):664–680. doi: 10.1039/c7tx00326a

Table 1. Dietary models of steatosis and steatohepatitis in rodents.

Models Kcal from fat in diet Added sugars in water Treatment duration (week) Obesity Insulin resistance Steatosis Lobular inflammation Hepatocytes ballooning Perisinusoidal fibrosis HCC Ref.
MCD 20% Up to 52 + + + + 48
CD-HFD NP 48 + NP + + + + + 49
HFD 60% Up to 50 + + + + + 50
HFTFD 58% + 16 + + + + + + 58
ALIOS 45% + Up to 16 + + + + + 54
HFD32 64% 60 + + + + + + 50
AMLN 40% + Up to 30 + + + + + + 56
WD 42% Up to 60 + + + + + + 52
WD 42% + Up to 52 + + + + + + + 58