Table 5. Diagnostic performance of the different imaging parameters using the proposed cut-offs* for the prediction of pancreatic insufficiency in CF patients.
Sensitivity (95% CI) |
Specificity (95% CI) |
Accuracy (95% CI) |
Cutoff | ||
---|---|---|---|---|---|
US | LP | 90 (56–100) | 73 (50–89) | 0.77 (0.61–0.94) | >1.3 |
VP | 55 (21–86) | 95 (76–100) | 0.87 (0.73–1) | >1.8 | |
VAS | 90(56–100) | 69 (48–86) | 0.83 (0.69–0.96) | >2.5 | |
MRI | FW/FSF | 100 (69–100) | 100 (86–100) | 1(1–1) | >1.1/0.4 |
ADC | 89 (52–100) | 100 (87–100) | 0.98 (0.94–1) | 677 |
Cutoff values were defined by highest Youden Index. ADC: Apparent diffusion coefficient, CI, confidence interval, FSF: Fat-signal fraction, FW: Fat water ratio LP/VP: Liver/pancreas and Vessel/ pancreas echo intensity ratios, MRI: Magnetic resonance imaging, US: Ultrasonography. ADC: Apparent diffusion coefficient