Table 3. Simulated/Experimental ratio for [Ca2+] in μM for WT and CSQ-KO fibers, assuming the amount bound by secondary buffer capacity at 10% or at 20%.
60 Hz | 20 Hz | 5 Hz | 1Hz | ||
---|---|---|---|---|---|
WT 10% | Cyto | 0.98 | 0.79 | 0.84 | 1.17 |
Mito | 1.04 | 0.88 | 0.94 | 0.51 | |
SR | 0.99 | 0.95 | 1.08 | 1.06 | |
CSQ-KO 10% | Cyto | 0.81 | 0.75 | 0.90 | 1.21 |
Mito | 0.83 | 0.88 | 0.76 | 0.58 | |
SR | 0.64 | 0.82 | 0.99 | 1.02 | |
CSQ-KO 20% | Cyto | 0.93 | 0.82 | 0.93 | 1.22 |
Mito | 1.34 | 1.22 | 0.90 | 0.59 | |
SR | 0.86 | 1.02 | 1.12 | 1.06 |