Table 1. Participant characteristics and endpoints.
Maltodextrin | Oligofructose | |||||
---|---|---|---|---|---|---|
Number of subjects | 18 | 19 | ||||
Age (years) | 23.5 (2.9) | 26.5 (12.2) | ||||
Gender (M/F) | 14/4 | 11/8 | ||||
Height (m) | 1.69 (0.09) | 1.73 (0.11) | ||||
Weight (kg) | 67.8 (13.6) | 67.7 (10.1) | ||||
Body Mass Index (kg/ m2) | 23.5 (2.9) | 22.5 (2.9) | ||||
Supplement compliance (%) | 104 (range 91–133) | 117 (range 105–132) | ||||
BL | PI | p-value | BL | PI | p-value | |
Total colonic Volume (ml) | 650 (179) | 740 (242) | 0.04 | 693 (151) | 802 (146) | 0.01 |
ascending (ml) | 219 (53) | 233 (67) | 0.34 | 238 (66) | 273 (72) | 0.01 |
transverse (ml) | 259 (105) | 307 (140) | 0.07 | 273 (83) | 317 (86) | 0.03 |
distal (ml) | 171 (73) | 201 (87) | 0.14 | 180 (59) | 206 (52) | 0.05 |
sigmoid | 0 (0) | 0 (0) | - | 3 (11) | 8 (33) | 0.33 |
Transit Score (a.u.) | 2.09 (1.40) | 2.05 (1.44) | 0.82 | 1.51 (0.73) | 1.33 (1.07) | 0.24 |
Breath Hydrogen (ppm) | 16.8 (12.8) | 6.3 (6.3) | 0.006 | 19.8 (23.4) | 36.3 (32.2) | 0.08 |
Breath Methane (ppm) | 20.6 (30.5) | 20.0 (33.7) | 0.86 | 19.7 (26.1) | 14.6 (26.5) | 0.24 |
Demographic and study endpoint data for study participants. There was no statistical difference between the study groups at baseline. BL = baseline, PI = post-intervention. Data shown as mean (SD) with no adjustment made for multiple comparisons.