Table 1. Estimated mean and 95% confidence interval of each group for spontaneous motor activity analysis.
| Actimeter parameters (frequency) |
Time (day) |
Group Mean (95% CI) |
||
|---|---|---|---|---|
| Control (n = 4) | Sham (n = 4) | Tumor (n = 4) | ||
| S-MOV | 0 | 338.8 (320.8; 357.7) | 374.5 (355.6; 394.4) | 343.0 (325.0; 362.0) |
| 7 | 324.0 (306.5; 342.5) | 362.0 (343.5; 381.5) | 301.0 (284.1; 318.9) *§ | |
| 14 | 311.2 (294.1; 329.4) | 345.0 (326.9; 364.1) | 283.0 (266.7; 300.3) *§ | |
| 21 | 314.5 (297.2; 332.8) | 290.3 (273.7; 307.8) * | 220.8 (206.4; 236.1) *#§ | |
| 28 | 314.7 (297.5; 333.0) | 280.8 (264.5; 298.0) * | 160.8 (148.6; 173.9) *#§ | |
| F-MOV | 0 | 951.5 (902.1; 1003.6) | 923.0 (874.3; 974.4) | 990.2 (939.8; 1043.4) |
| 7 | 938.7 (889.7; 990.5) | 956.8 (907.2; 1009.0) | 890.3 (842.5; 940.7) | |
| 14 | 940.8 (891.6; 992.6) | 980.8 (930.6; 1033.7) | 760.8 (716.7; 807.5) *#§ | |
| 21 | 924.0 (875.3; 975.4) | 850.3 (803.6; 899.6) | 282.0 (255.7; 311.0) *#§ | |
| 28 | 810.3 (764.7; 858.5) * | 760.8 (716.7; 807.5) * | 171.3 (151.0; 194.2) *#§ | |
| S-STE | 0 | 178.5 (169.0; 188.5) | 157.5 (148.6; 166.9) | 190.3 (180.5; 200.5) § |
| 7 | 179.5 (170.0; 189.5) | 188.3 (178.5; 198.5) | 180.8 (171.2; 190.8) | |
| 14 | 190.2 (180.5; 200.5) | 174.5 (165.2; 184.4) | 147.0 (138.4; 156.1) *#§ | |
| 21 | 177.5 (168.1; 187.5) | 159.5 (150.6; 169.0) | 120.8 (113.0; 129.0) *#§ | |
| 28 | 171.3 (162.0; 181.0) | 162.0 (153.0; 171.5) | 88.0 (81.4; 95.1) *#§ | |
| F-STE | 0 | 537.8 (508.0; 569.2) | 543.0 (513.1; 574.6) | 531.2 (501.7; 562.6) |
| 7 | 637.7 (605.3; 672.0) | 600.7 (569.3; 634.0) | 500.8 (472.1; 531.2) #§ | |
| 14 | 615.5 (583.6; 649.1) | 580.8 (549.8; 613.4) | 533.5 (503.9; 564.9) | |
| 21 | 520.7 (491.5; 551.8) | 590.3 (559.0; 623.2) | 420.8 (394.5; 448.7) *#§ | |
| 28 | 562.0 (531.6; 594.2) | 501.0 (472.3; 531.4) | 220.8 (202.0; 241.3) *#§ | |
| S-REA | 0 | 23.5 (20.7; 26.6) | 28.5 (25.4; 31.9) | 22.5 (19.8; 25.6) § |
| 7 | 26.5 (23.5; 29.8) | 22.5 (19.8; 25.6) | 15.5 (13.3; 18.1) #§ | |
| 14 | 24.5 (21.7; 27.7) | 20.5 (17.9; 23.4) * | 12.5 (10.5; 14.8) *#§ | |
| 21 | 22.5 (19.8; 25.6) | 21.5 (18.9; 24.5) * | 8.5 (6.9; 10.5) *#§ | |
| 28 | 25.5 (22.6; 28.8) | 22.5 (19.8; 25.6) | 5.3 (4.0; 6.8) *#§ | |
| F-REA | 0 | 30.5 (27.4; 33.9) | 27.5 (24.6; 30.8) | 28.5 (25.5; 31.8) |
| 7 | 24.5 (21.8; 27.6) | 22.5 (19.9; 25.5) | 25.5 (22.7; 28.6) | |
| 14 | 19.5 (17.1; 22.3) * | 24.5 (21.8; 27.6) | 15.5 (13.4; 18.0) *§ | |
| 21 | 20.5 (18.0; 23.3) * | 18.5 (16.1; 21.2) * | 12.5 (10.6; 14.8) *# | |
| 28 | 22.5 (19.9; 25.5) | 19.5 (17.1; 22.3) | 7.5 (6.1; 9.3) *#§ | |
Abbreviations: S-MOV, slow movement; F-MOV, fast movement; S-STE, slow stereotypic; F-STE, fast stereotypic; S-REA, slow rearing; F-REA, fast rearing.
Multiple comparison analysis corrected by Bonferroni for time and groups.
* p < 0.001 in comparison with base time
# p < 0.001 in comparison with control group
§ p < 0.001 in comparison with sham group