Table 3. Descriptives for Hao Hao’s (SB741) 2016 reproductive cycle: USpG-, creatinine-corrected and raw metabolite concentration, USpG-values and creatinine concentrations in urine and faecal output.
| Pro-oestrus (D-8 -D0) |
Postoestrus (D0—D6) |
Primary P4 rise (D7—D76) |
Secondary P4 rise (D77-D114) |
Post Birth (D119-D125) |
||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Mean (stdev) | Median (range) | Mean (stdev) | Median (range) | Mean (stdev) | Median (range) | Mean (stdev) | Median (range) | Mean (stdev) | Median (range) | |
| Oestrogens | (n = 28/28) | (n = 17/17) | (n = 64/65) | (n = 49/49) | (n = 5/5) | |||||
| USpG (ng/mL) | 83.41 (61.31) | 63.03 (31.61–306.5)b | 27.46 (24.87) | 16.86 (2.62–88.82)a | 2.67 (1.19) | 2.42 (0.85–6.80)a | 6.61 (3.62) | 5.82 (1.31–14.89)a | 2.43 (1.86) | 1.66 (0.50–5.29)a |
| Creatinine (ng/mg Cr) | 94.60 (55.13) | 80.71 (36.36–249.1)c | 41.83 (47.51) | 20.36 (3.57–189.7)b | 12.87 (33.76) | 6.63 (2.10–272.7)a,b | 8.07 (4.60) | 7.32 (2.88–30.46)a,b | 2.10 (0.81) | 1.84 (1.12–3.18)a |
| Raw (ng/ mL) | 84.18 (71.06) | 75.49 (16.33–391.0)b | 31.67 (26.96) | 21.48 (1.56–77.49)a | 1.99 (1.01) | 1.85 (0.46–4.82)a | 10.07 (8.71) | 6.72 (0.76–35.46)a | 6.89 (6.93) | 4.49 (0.54–18.14)a |
| Progesterone | (n = 28/28) | (n = 17/17) | (n = 64/65) | (n = 49/49) | (n = 5/5) | |||||
| USpG (ng/mL) | 3.00 (1.22) | 2.60 (1.63–7.27)a | 6.85 (2.78) | 5.90 (3.40–13.27)a | 14.39 (6.28) | 13.90 (5.69–37.54)a | 87.30 (43.85) | 86.40 (26.60–174.9)b | 6.22 (2.89) | 5.21 (3.80–10.99)a |
| Creatinine (ng/mg Cr) | 3.48 (1.04) | 3.21 (2.10–5.75)a | 12.67 (15.20) | 7.32 (4.94–67.26)a | 62.63 (127.5) | 32.43 (3.54–999.8)a,b | 129.83 (88.75) | 117.61 (19.87–372.9)b | 6.27 (1.40) | 5.76 (4.83–8.51)a |
| Raw (ng/ mL) | 2.95 (1.30) | 2.83 (0.71–6.81)a | 8.88 (7.02) | 6.12 (0.61–29.00)a | 9.77 (4.61) | 8.58 (0.92–18.94)a | 112.16 (74.17) | 93.30 (14.39–334.6)b | 16.26 (13.01) | 11.77 (4.11–37.64)a |
| Ceruloplasmin | (n = 28/28) | (n = 17/17) | (n = 64/65) | (n = 49/49) | (n = 5/5) | |||||
| USpG (ng/mL) | 6.50 (3.51) | 5.44 (1.73–15.55)b,c | 4.49 (2.62) | 4.69 (0.73–8.79)a,b | 10.18 (3.98) | 9.96 (2.44–19.18)c | 4.60 (3.49) | 3.63 (0.61–18.01)a,b | 0.71 (0.30) | 0.82 (0.19–0.91)a |
| Creatinine (ng/mg Cr) | 7.51 (3.97) | 6.87 (2.24–22.22)a,b | 12.72 (2.62) | 6.84 (0.47–98.47)a,b | 35.26 (35.21) | 29.19 (9.07–280.0)b | 10.45 (14.89) | 3.96 (0.49–56.72)a,b | 0.85 (0.70) | 0.68 (0.21–2.04)a |
| Raw (ng/ mL) | 6.28 (3.50) | 5.49 (2.03–14.02)b | 4.75 (3.16) | 3.23 (0.90–11.34)a,b | 7.69 (4.32) | 6.41 (2.73–20.42)b | 4.59 (2.33) | 4.34 (1.20–12.47)a,b | 1.71 (1.06) | 1.93 (0.35–3.06)a |
| PGFM | (n = 28/28) | (n = 17/17) | (n = 29/65) | (n = 49/49) | (n = 5/5) | |||||
| USpG (ng/mL) | 14.03 (8.52) | 12.38 (2.51–34.82)a | 15.52 (11.34) | 14.47 (3.10–52.40)a | 2.75 (1.02) | 2.72 (1.21–6.34)a | 119.58 (254.71) | 26.64 (2.07–1344)a | 40.76 (25.98) | 33.37 (9.52–76.92)a |
| Creatinine (ng/mg Cr) | 17.54 (12.38) | 13.44 (3.71–46.06)a | 24.03 (17.73) | 18.66 (7.07–66.55)a | 10.02 (8.43) | 7.11 (2.98–45.12)a | 92.87 (171.48) | 24.96 (5.99–857.3)a | 36.34 (10.68) | 36.87 (20.77–46.16)a |
| Raw (ng/ mL) | 13.70 (9.30) | 11.43 (2.71–39.95)a | 24.50 (34.69) | 19.18 (0.61–151.2)a | 2.12 (1.26) | 1.70 (0.81–5.61)a | 281.53 (767.56) | 38.61 (1.23–4605)a | 112.18 (98.34) | 77.35 (10.03–263.6)a |
| USpG | (n = 28/28) | (n = 17/17) | (n = 65/65) | (n = 49/49) | (n = 5/5) | |||||
| USpG | 1.006 (0.003) | 1.006 (1.002–1.011)a,b | 1.007 (0.004) | 1.007 (1.001–1.016)b | 1.004 (0.002) | 1.004 (1.002–1.012)a | 1.007 (0.004) | 1.007 (1.002–1.019)b | 1.013 (0.005) | 1.015 (1.006–1.019) |
| Cr | (n = 28/28) | (n = 17/17) | (n = 64/65) | (n = 49/49) | (n = 5/5) | |||||
| Creatinine (mg/mL) | 0.90 (0.44) | 0.85 (0.26–1.92)a,b | 1.19 (1.10) | 0.92 (0.09–4.24)b,c | 0.29 (0.18) | 0.26 (0.01–0.82)a | 1.52 (1.34) | 1.07 (0.09–5.37)c | 2.70 (1.97) | 2.44 (0.48–5.71) |
| Faeces | (n = 6/28) | (n = 4/17) | (n = 61/65) | (n = 44/49) | ||||||
| Faeces (kg) | 4.97 (1.09) | 4.85 (3.70–6.60)a | 8.53 (2.48) | 9.30 (5.00–10.50)a,b | 12.64 (4.31) | 14.00 (3.70–22.00)b | 5.47 (6.38) | 2.80 (1.00–23.20)a | ||
Stdev = standard deviation; n = number of samples; USpG = urinary specific gravity; cr = creatinine.
a-c = different superscripts (a-c; ascending; horizontally) indicate significant differences for the respective metabolite levels between each defined reproductive period; Independent-Samples Kruskall Wallis test with post hoc Dunn’s comparison; significant if p < 0.05.