Table 7. Other intracellular changes in chondrocytes.

Ref.	Sources	Interventions		Outcomes
		T-2 toxin	Time
Alteration of DNA and proteins
Li et al. 200829	Human fetus	0.01 μg ml–1	5 d	DNA content↓
Cao et al. 199432	Rabbit	0.005, 0.01, 0.02 μg ml–1	4 d	DNA content↓, GLcUA content in matrix↓
Huo et al. 199830	Rabbit	0.0005, 0.001, 0.005 mg l–1	4 d	DNA content↓, protein content ↓
Wang et al. 200656	Wistar rat	1, 10, 100 μg l–1	24 h	DNA damage↑
Mitochondria damage
Liu et al. 201440	Human	1, 10, 20 ng ml–1	5 d	Citrate synthase (–), complexes I, II (–), III–V↓, ΔΨm↓, ATP↓, ROS↑, GSH↓, GPx↓
Li et al. 199336	Chick embryo	0.004, 0.01, 0.04 ppm	5 d	H+-ATP enzyme↓, cytochrome C oxidase↓, succinate dehydrogenase (–)
Li et al. 199335	Chick embryo	0.01 ppm	5 d	H+-ATP enzyme↓, cytochrome C oxidase↓, succinate dehydrogenase (–)
Lin et al. 199437	Chick embryo	0.004, 0.01, 0.04 ppm	4 d	H+-ATP enzyme↓, cytochrome C oxidase↓, succinate dehydrogenase (–)
Oxidative stress
He et al. 201146	Broiler chicken	5, 50, 500 nmol l–1	48 h	ROS↑, MDA↑, CAT↑, SOD↑, ALP↓, GSH↓
Tian et al. 201249	Murine (ATDC5)	10, 20, 40 μg l–1	1–24 h	ROS↑
NO synthesis
Chen et al. 200628	Human fetus	1, 10, 20 ng ml–1	2 d, 5 d	NO↑, iNOS↑
Yang et al. 200857	Human fetus	1, 10, 20 μg l–1	2 d, 5 d	NO↑, iNOS↑