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. 2017 Sep 28;6(6):930–946. doi: 10.1039/c7tx00152e

Table 1. Target and actual nicotine concentrations in 3R4F smoke or THS2.2 aerosol dilutions.

  Experimental repetitions Experiment 1 Experiment 2 Experiment 3
3R4F (0.15) Target nicotine concentration (mg L–1) 0.15 0.15 0.15
Applied dilution in Vitrocell® (vol/vol) 7% 7% 7%
Actual nicotine measured in EXtrelut® (mg L–1) 0.14 ± 0.00 (N = 3) 0.16 ± 0.01 (N = 3) 0.16 ± 0.01 (N = 3)
3R4F (0.26) Target nicotine concentration (mg L–1) 0.26 0.26 0.26
Applied dilution in Vitrocell® (vol/vol) 13% 13% 13%
Actual nicotine measured in EXtrelut® (mg L–1) 0.22 ± 0.01 (N = 3) 0.23 ± 0.01 (N = 3) 0.32 ± 0.02 (N = 3)
THS2.2 (0.14) Target nicotine concentration (mg L–1) 0.14 0.14 0.14
Applied dilution in Vitrocell® (vol/vol) 13% 13% 13%
Actual nicotine measured in EXtrelut® (mg L–1) 0.11 ± 0.01 (N = 3) 0.17 ± 0.02 (N = 3) 0.15 ± 0.00 (N = 3)
THS2.2 (0.30) Target nicotine concentration (mg L–1) 0.30 0.30 0.30
Applied dilution in Vitrocell® (vol/vol) 24% 24% 24%
Actual nicotine measured in EXtrelut® (mg L–1) 0.29 ± 0.01 (N = 3) 0.34 ± 0.02 (N = 3) 0.29 ± 0.02 (N = 3)
THS2.2 (0.45) Target nicotine concentration (mg L–1) 0.45 0.45 0.45
Applied dilution in Vitrocell® (vol/vol) 31% 31% 31%
Actual nicotine measured in EXtrelut® (mg L–1) 0.45 ± 0.01 (N = 3) 0.48 ± 0.01 (N = 3) 0.41 ± 0.02 (N = 3)