NREM sleep and REM sleep in mice after cessation of exposure to 1 h/1 h white light (WL) or red light (RL) at 10 lx/D. (a) Time course changes of NREM sleep and REM sleep in mice after ending exposure to 1 h/1 h WL at 10 lx/D. Each cycle represents the hourly mean±SEM of NREM sleep and REM sleep. White and blue circles indicate the profiles of the baseline day and the day after cessation of exposure to 1 h/1 h WL at 10 lx/D, respectively. The horizontal open and filled bars on the x axes indicate the 12-h dark and 12-h light periods, respectively. *P<0.05, **P<0.01 compared with baseline, assessed via two-way ANOVA followed by a Bonferroni test. (b) Total time spent in NREM sleep and REM sleep during the first 2 h of the dark phase after cessation of 1 h/1 h WL at 10 lx/D. (c) Time course changes of NREM sleep and REM sleep in mice after cessation of exposure to 1 h/1 h RL at 10 lx/D. Each cycle represents the hourly mean±SEM of NREM sleep and REM sleep. White and red circles indicate the profiles of the baseline day and the day after ending exposure to 1 h/1 h RL at 10 lx/D, respectively. The horizontal open and filled bars on the x axes indicate the 12-h dark and 12-h light periods, respectively. Data shown are assessed via two-way ANOVA followed by a Bonferroni test. (d) Total time spent in NREM sleep and REM sleep during the entire day, 12-h light phase and 12-h dark phase of the baseline day and the day after cessation of exposure to 1 h/1 h RL at 10 lx/D, respectively. Values are means±SEM (n=4). No significant difference compared with the baseline, assessed via a two-tailed paired t-test.