Table 1.
Baseline characteristics of newly treated hypertensive patients by status of being a false positive self-reported adherer to prescribed drug treatment.
| Type of self-reported measurement of adherence | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| MARS | Previous Month Adherence | Previous Week Adherence | |||||||
| Concordanta (n=104) |
False positive adhererb (n=39) |
Concordanta
n=111) |
False positiveb adherer (n=41) |
Concordanta (n=107) |
False positive adhererb (n=42) |
||||
| Participant characteristics | Mean (SD) | Mean (SD) | P-value | Mean (SD) | Mean (SD) | P-value | Mean (SD) | Mean (SD) | P-value |
| Age (years) | 49.8 (9.9) | 49.4 (11.9) | 0.81 | 50.1 (9.8) | 49.8 (11.7) | 0.84 | 50.1 (10.1) | 50 (11.1) | 0.95 |
| Male (%) | 57.7 | 53.8 | 0.68 | 59.5 | 53.7 | 0.52 | 60.7 | 52.4 | 0.35 |
| Whites (%) | 86.5 | 92.3 | 0.35 | 88.3 | 87.8 | 0.93 | 87.9 | 88.1 | 0.97 |
| Education (<high school) (%) | 20.2 | 30.8 | 0.18 | 22.5 | 29.3 | 0.39 | 20.6 | 33.3 | 0.1 |
| Married (%) | 75.7 | 79.5 | 0.64 | 76.6 | 77.5 | 0.91 | 78.5 | 73.2 | 0.91 |
| Income (<$16,000) (%) | 5.8 | 2.6 | 0.43 | 6.3 | 4.9 | 0.74 | 6.5 | 4.8 | 0.68 |
| Heavy Drinkerc (%) | 29.8 | 41 | 0.21 | 28.8 | 43.9 | 0.08 | 29 | 42.9 | 0.11 |
| Current Smoker (%) | 12.5 | 7.7 | 0.42 | 13.5 | 7.3 | 0.3 | 13.1 | 9.5 | 0.55 |
| Poor/fair general health status (%) | 6.7 | 10.3 | 0.48 | 3.6 | 14.6 | 0.01 | 3.7 | 14.3 | 0.02 |
| BP drug copayment (%) | 88.9 | 83.8 | 0.43 | 90.4 | 82.1 | 0.17 | 90 | 82.5 | 0.22 |
| More than 1 BP pill (%) | 23.1 | 33.3 | 0.22 | 27 | 31.7 | 0.57 | 27.1 | 31 | 0.64 |
| Number of BP drug side effects | 5.5 (5.1) | 4.5(4.0) | 0.32 | 5.0 (4.8) | 5.0 (4.9) | 0.94 | 5.1 (4.8) | 5.1 (4.9) | 0.99 |
| At least 1 BP drug side effects (%) | 88.5 | 82.1 | 0.32 | 86.5 | 82.9 | 0.58 | 86.9 | 83.3 | 0.57 |
| Over all symptom distress scored | 15.0 (22.8) | 13.7(32.9) | 0.78 | 13.8 (22.2) | 13.9 (32.5) | 0.97 | 14.1 (22.5) | 14.1 (32.1) | 0.99 |
| Medication for other diseases (%) | 12.5 | 10.3 | 0.71 | 11.7 | 9.8 | 0.74 | 12.2 | 9.5 | 0.65 |
| Anxiety score (PGWB) | 5.9 (3.6) | 6.9(4.3) | 0.15 | 5.7 (3.5) | 7.0 (4.2) | 0.06 | 5.7 (3.5) | 7.1 (4.3) | 0.03 |
| Depression score (BDI-II) | 4.6 (6.6) | 4.5(5.5) | 0.93 | 4.1 (6.3) | 5.0 (6.0) | 0.4 | 4.3 (6.5) | 5.1 (6.0) | 0.46 |
| Systolic BP (mm Hg) | 135.3 (15.0) | 132.3(15.2) | 0.29 | 135 (15.1) | 133.2 (15.3) | 0.51 | 135.4 (15.0) | 133.1 (15.2) | 0.39 |
| Diastolic BP (mm Hg) | 85.7 (10.4) | 82.1(10.7) | 0.07 | 85.4 (9.8) | 82.5 (10.6) | 0.12 | 85.5 (10.3) | 82.6 (10.5) | 0.14 |
Abbreviations: BP, blood pressure; BDI-II, Beck Depression Inventory-II; MARS, Medication adherence report scale; PGWB, Psychological General Well- Being Index; SD, Standard Deviation.
Concordants are individuals who were classified into the same adherence category by both pill count adherence ratio (PCAR) and the self-reported measurement of medication adherence.
False positive adherers are individuals who were non-adherers based on PCAR (<80%) but adherers based on self-reported measurement of adherence.
Heavy drinkers were participants who had >14 drinks/week for males and >7 drinks/week for females.
Overall symptom distress scores was calculated by multiplying the presence, severity and frequency of each side effect symptom and summing the resulting values for all side effect symptoms.