Fig. 3. Changes in mitochondrial membrane potential in offspring hippocampal neurons at postnatal day 21 following the exposure of pregnant mice to nano-TiO2. (a) Representative confocal images showing mitochondrial injury in the hippocampal neurons of the control and nano-TiO2-treated groups. (b) Levels of membrane potential, as indicated by the ratio of red to green fluorescence intensity, in the hippocampal neurons of the control and nano-TiO2-treated groups. Letters b and a indicate significant difference between the group treated with 1 mg per kg BW nano-TiO2 and the control (p < 0.05); letters c and b indicate significant difference between the groups treated with 2 and 1 mg per kg BW nano-TiO2 (p < 0.05); letters d and c indicate significant difference between the groups treated with 3 and 2 mg per kg BW nano-TiO2 (p < 0.05). Values represent mean ± SD (N = 5).
