Table 1. DNA damage evaluated under alkaline conditions (ssb + dsb) and under neutral conditions (dsb) in MCF-7 cells after 12 h of LDCD treatment (A) and post recovery for 24 h (B) ^a .

Treatment	A	B
(i) Alkaline condition (ssb + dsb)
Vehicle control	1.5 ± 0.4	1.7 ± 0.5
DOX
1 μM	9.1 ± 0.6*	6.5 ± 1.2
2 μM	13.0 ± 1.5*	8.2 ± 0.6*
10 μM	27.3 ± 1.0*	17.6 ± 2.6*
ETOP
0.5 μM	9.4 ± 0.8*	7.1 ± 0.5
1 μM	12.1 ± 0.9*	7.0 ± 0.8*
5 μM	22.8 ± 1.3*	17.5 ± 1.6*
BUS
40 μM	8.2 ± 0.4*	5.8 ± 0.4
80 μM	10.8 ± 0.6*	7.7 ± 0.9
400 μM	19.6 ± 0.4*	14.6 ± 1.4*
(ii) Neutral condition (dsb)
Vehicle control	0.9 ± 0.2	1.0 ± 0.2
DOX
1 μM	6.3 ± 1.0*	6.9 ± 0.9*
2 μM	11.2 ± 0.6*	5.5 ± 0.3*
10 μM	15.5 ± 2.0*	11.7 ± 1.2*
ETOP
0.5 μM	5.6 ± 0.2*	6.3 ± 1.4*
1 μM	8.5 ± 0.9*	6.8 ± 0.8*
5 μM	13.0 ± 1.2*	13.8 ± 1.2*
BUS
40 μM	5.0 ± 0.6*	2.9 ± 0.3
80 μM	8.8 ± 0.6*	4.9 ± 0.8
400 μM	14.5 ± 1.2*	13.8 ± 1.8*

^aAll values are (mean of three independent experiments) ± (standard error of the mean).