Table 1. Oxy-PAHs used in this study with abbreviations, CAS numbers, molecular weight (MW), logarithm of octanol-water partition coefficient (log Kow) and inhibition of CYP1A1-mediated EROD activity (IC50 with 95% CI).
| Oxy-PAHs | Abbr. | CAS no. | MW (g mol–1) | log Kow a | IC50 (μM) | 95% CI b |
| 1-Indanone | 1-INO | 83-33-0 | 132.2 | 2.11 | >10 | — |
| 1H-Phenalen-1-one | 1H-PHO | 548-39-0 | 180.2 | 3.39 | >10 | — |
| 9-Fluorenone | 9-FLO | 486-25-9 | 180.2 | 3.58 | 3.0 | 2.3–4.0 |
| Acenaphthylene-1,2-quinone | 1,2-ACNQ | 82-86-0 | 182.2 | 1.95 | >10 | — |
| 4H-Cyclopenta[def]phenanthrene-4-one | 4H-CPO | 5737-13-3 | 204.2 | 4.14 | 0.32 | 0.27–0.39 |
| Phenanthrene-9,10-quinone | 9,10-PQ | 84-11-7 | 208.2 | 2.52 | 0.65 | 0.50–0.86 |
| Anthracene-9,10-quinone | 9,10-AQ | 84-65-1 | 208.2 | 3.39 | >10 | — |
| 2-Methylanthracene-9,10-quinone | 2-MAQ | 84-54-8 | 222.2 | 3.89 | 4.9 | 3.5–6.9 |
| 7H-Benz[de]anthracene-7-one | 7H-BAO | 82-05-3 | 230.3 | 4.81 | 0.77 | 0.62–0.96 |
| Benzo[a]fluorenone | BFLO | 479-79-8 | 230.3 | 4.73 | 0.061 | 0.049–0.075 |
| 2,3-Dimethylanthracene-9,10-quinone | 2,3-DMAQ | 20054-39-1 | 236.3 | 4.44 | 2.1 | 1.3–3.2 |
| 6H-Benzo[cd]pyren-6-one | 6H-BPO | 3074-00-8 | 254.3 | 5.31 | 0.44 | 0.32–0.62 |
| Chrysene-1,4-quinone | 1,4-CHRQ | 100900-16-1 | 258.3 | 4.01 | 6.2 | 4.8–8.0 |
| Naphthacene-5,12-quinone | 5,12-NQ | 1090-13-7 | 258.3 | 4.52 | 2.5 | 1.5–4.1 |
| Benz[a]anthracene-7,12-quinone | 7,12-BAQ | 2498-66-0 | 258.3 | 4.40 | 0.037 | 0.021–0.065 |
aEstimated using KOWWIN in EPI suite v 4.11, US Environmental Protection Agency.
b95% confidence interval of IC50 values.