Table 3. Effect of resveratrol and pterostilbene on the gene expressions and mitochondrial content of heart tissue in AEST administered rats.

Heart mRNA levels (arbitrary units)
Parameters	Control	VCD	AEST	ET	RSV 5	RSV 20	RSV 40	PT 5	PT 20	PT 40	CT
SIRT 1	1.00 ± 0.07	0.55 ± 0.03a	0.37 ± 0.01a	0.93 ± 0.02b,c	1.32 ± 0.19b,c	1.44 ± 0.08b,c	4.23 ± 0.29b,c	0.45 ± 0.05	0.43 ± 0.07	0.48 ± 0.09	0.90 ± 0.03c
PGC-1α	1.00 ± 0.02	0.56 ± 0.05	0.45 ± 0.02a	0.97 ± 0.01c	0.91 ± 0.03c	0.98 ± 0.04c	1.06 ± 0.07c	0.76 ± 0.05	0.94 ± 0.11c	1.17 ± 0.10c	2.44 ± 0.33c
PPAR-α	1.00 ± 0.06	0.52 ± 0.03	0.41 ± 0.03	1.08 ± 0.08	1.33 ± 0.02	1.57 ± 0.11	3.01 ± 0.25b,c	1.74 ± 0.10	2.64 ± 0.23b,c	7.47 ± 0.66b,c	10.2 ± 0.99b,c
NRF-1	1.00 ± 0.03	0.76 ± 0.04	0.32 ± 0.04	8.91 ± 0.96b,c	2.36 ± 0.15b,c	4.38 ± 0.51b,c	6.24 ± 0.26b,c	2.80 ± 0.27b,c	5.67 ± 0.15b,c	5.96 ± 0.37b,c	7.48 ± 0.21b,c
TFAM	1.00 ± 0.04	0.63 ± 0.06	0.41 ± 0.03a	0.95 ± 0.02c	0.82 ± 0.02	0.85 ± 0.04	1.07 ± 0.06c	0.79 ± 0.05	1.18 ± 0.22c	1.34 ± 0.22c	2.70 ± 0.23c
Mitochondrial content (nDNA/mtDNA)	1.00 ± 0.07	0.86 ± 0.04	0.61 ± 0.04a	0.93 ± 0.02c	0.84 ± 0.02c	0.95 ± 0.02c	1.19 ± 0.09c	0.75 ± 0.02	0.93 ± 0.02c	1.13 ± 0.06c	1.44 ± 0.05c