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. 2018 Jan 10;7(2):271–282. doi: 10.1039/c7tx00262a

Table 3. Exposure to PM2.5 induces expression of fibrosis related molecules in the livers of rats in different groups.

Groups (mg kg–1) MMP13 Col I Col III TGF-β1
mRNA expressions in livers
0 1.00 ± 0.51 1.00 ± 0.31 1.00 ± 0.32 1.00 ± 0.25
0.2 1.15 ± 0.36 1.29 ± 0.46 1.27 ± 0.26 1.24 ± 0.23
0.6 1.54 ± 0.56 1.33 ± 0.43 1.48 ± 0.38 1.36 ± 0.27
1.5 2.21 ± 0.63** 1.58 ± 0.45* 1.66 ± 0.60* 1.51 ± 0.29*
r 0.99 0.92 0.92 0.91
0.3 1.64 ± 0.59 1.39 ± 0.20 1.50 ± 0.40 1.28 ± 0.44
1.5 2.16 ± 0.43** 1.64 ± 0.57* 1.69 ± 0.23** 1.46 ± 0.40*
2.7 2.33 ± 0.88** 1.78 ± 0.30** 1.71 ± 0.42** 1.62 ± 0.40**
r 0.90 0.91 0.79 0.93
Groups Protein expressions in livers
0 1.00 ± 0.15 1.00 ± 0.26 1.00 ± 0.26 53.88 ± 17.52
0.2 1.12 ± 0.21 1.46 ± 0.52 1.12 ± 0.16 57.19 ± 22.90
0.6 1.29 ± 0.31 1.73 ± 0.37 1.34 ± 0.55 77.58 ± 21.00
1.5 1.49 ± 0.25* 1.92 ± 0.42* 1.70 ± 0.43* 81.62 ± 26.79*
r 0.98 0.88 0.99 0.89
0.3 1.16 ± 0.13 1.63 ± 0.46 1.19 ± 0.39 56.24 ± 18.26
1.5 1.44 ± 0.28* 1.84 ± 0.46* 1.77 ± 0.43* 67.37 ± 14.40
2.7 1.59 ± 0.17** 2.0 ± 0.38* 1.89 ± 0.31* 86.80 ± 22.80*
r 0.98 0.84 0.95 0.99
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